Quote: "Blinding of the allocation to treatments was not possible."Ĭomment: agents had different appearances.īlinding of outcome assessment (detection bias) Random sequence generation (selection bias)Ĭomputer‐generated randomisation sequence.īlinding of participants and personnel (performance bias) Study author conflicts of interest statements: not declared. Included in network meta‐analysis for pleurodesis failure and fever. Unpublished data obtained from authors relating to subgroup of participants in the study with MPE – only these data were included for the purposes of this review. Pleurodesis success according to need for thoracentesis (CR: relief of symptoms related to the effusion and no re‐accumulation on CXR at 30 days PR: reduced dyspnoea related to effusion with only partial re‐accumulation of fluid on CXR and no requirement for therapeutic thoracentesis failure: lack of success as defined above)
Drain removed when < 100 mL/day output.įollow‐up at 1 week, 1 month, 3 months and 6 months, and then every 3 months thereafter. Inclusion criteria: recurrent symptomatic pleural effusion with improvement of breathlessness with thoracentesis or primary or secondary pneumothorax.Įxclusion criteria: allergy to iodine thyroid disorder trapped lung air leak advanced malignancy with expected survival 250 mL/day drainage.
Single‐centre RCT comparing the efficacy of cosmetic talc with iodopovidone for pleurodesis (India).
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